The story of the relationship between Karamakate, an Amazonian shaman and last survivor of his people, and two scientists who work together over the course of 40 years to search the Amazon for a sacred healing plant. 

After Ferdinand, a bull with a big heart, is mistaken for a dangerous beast, he is captured and torn from his home. Determined to return to his family, he rallies a misfit team on the ultimate adventure.

In Persia in the 11th Century, a surgeon's apprentice disguises himself as a Jew to study at a school that does not admit Christians.